East Wheeling Beyond Marketing January 19, 2021 East Wheeling is the neighborhood that is located directly east of Downtown. While much of the neighborhood is made up of residential row houses and a few apartment buildings, it is balanced by numerous other institutions and businesses. As a National Historic District, there are numerous historic buildings throughout the neighborhood, especially of the Victorian era. East Wheeling also has a strong Catholic history and presence as the home of the Diocese of Wheeling-Charleston.